- 青琳森
- 電子郵件：qingls@cib.ac.cn
- 職 稱：研究員
- 學 歷：博士研究生
個人簡歷
青琳森，男，1981年9月生，四川南充人，執業藥師，研究員、博士生導師
教育經歷：?
1999.9 - 2003.6? 華西醫科大學，藥學院，藥學專業本科?
2003.9 - 2006.6? 四川大學，華西藥學院，生藥學專業碩士?
2008.9 - 2011.6? 中國科學院成都生物研究所，藥物化學專業博士?
工作經歷：?
2006.7 - 2008.8? 成都地奧制藥集團，藥物研究所?
2011.7 - 2013.6? 中國科學院成都生物研究所，博士后?
2013.7至今?????? 中國科學院成都生物研究所，副研究員、研究員
研究方向
天然活性成分研究與新藥開發?
社會任職
四川省藥學會中藥與天然藥專委會委員
四川省分析測試學會有機質譜專委會理事
中國人民政治協商會議成都市第十六屆委員會委員
獲獎及榮譽
?
承擔科研項目情況
主持：?
1. 中央引導地方科技發展資金項目，2022.9-2023.8?
2. 四川省科技計劃國際/港澳臺科技創新合作項目，2022.1-2023.12?
3. 中國科學院戰略生物資源服務網絡計劃活性天然化合物發現、評價與轉化平臺項目，2021.10-2024.12?
4. 浙江佐力藥業股份有限公司委托項目，2021.3-2024.3?
5. 四川省科技計劃重點研發項目，2019.1-2020.12?
6. 中國科學院西部青年學者（院內A類）項目，2019.1-2021.12?
7. 中國科學院戰略生物資源服務網絡計劃活性天然化合物發現、評價與轉化平臺項目，2018.8-2021.7?
8. 中國博士后科學基金第6批特別資助，2013.6-2016.6?
9. 中國科學院西部博士人才培養計劃，2013.1-2016.6?
10. 國家自然科學基金青年基金，2013.1-2015.12?
11. 中國博士后科學基金第50批面上資助，2011.9-2013.12?
同時參與國家自然科學基金、四川省科技計劃、香港特區政府衛生署項目、澳門科學技術發展基金等多項課題的研究。?
代表論著
科研論文（一作/通訊，含并列）：
1. Xiao-Feng Huang, et al. Chemical derivatization strategies for enhancing HPLC analytical performance of natural active triterpenoids. Journal of Pharmaceutical Analysis. 2024, 14(3): 295-307.
2. Xiao-Yi Chen, et al. Preclinical investigations on anti-fibrotic potential of long-term oral therapy of sodium astragalosidate in animal models of cardiac and renal fibrosis. ACS Pharmacology & Translational Science. 2024, 7(2): 421-431.
3. Shan-Shan Song, et al. Role of simulated in vitro gastrointestinal digestion on biotransformation and bioactivity of astragalosides from Radix Astragali, Journal of Pharmaceutical and Biomedical Analysis, 2023, 231: 115414.
4. Qian-Long Wang, et al. Surface hydrolysis-designed AuNPs-zwitterionic-glucose as a novel tool for targeting macrophage visualization and delivery into infarcted hearts, Journal of Controlled Release, 2023, 356: 678-690.
5. Lin-Sen Qing, et al. Microfluidic strategies for natural products in drug discovery: Current status and future perspectives. Trends in Analytical Chemistry, 2023, 158: 116832.
6. You-Jiao Wu, et al. Elucidation of the binding mechanism of astragaloside IV derivative with human serum albumin and its cardiotoxicity in zebrafish embryos. Frontiers in Pharmacology, 2022, 13: 987882.
7. Tian-Tian Wang, et al. Nanomaterial-based optical- and electrochemical-biosensors for urine glucose detection: A comprehensive review. Advanced Sensor and Energy Materials, 2022, 1(3): 100016.
8. Qian-Long Wang, et al. Non-invasion prognosis of post-myocardial infarction using urinary miRNA ultra-trace detection based on single target DNA functionalized AuNPs. ACS Applied Materials & Interfaces, 2022, 14(3): 3633-3642.
9. Ming-Qing Tang, et al. Advances in aptamer-based sensing assays for C-reactive protein. Analytical and Bioanalytical Chemistry, 2022, 414(2): 867-884.
10. Jing Xie, et al. Determination of nine nucleosides in Rhizoma Paridis by quantitative analysis of multi-components via a single marker method. Journal of Separation Science, 2021, 44(9): 1866-1874.
11. Li Chen, et al. Astragaloside IV derivative (LS-102) alleviated myocardial ischemia reperfusion injury by inhibiting Drp1Ser616 phosphorylation-mediated mitochondrial fission. Frontiers in Pharmacology, 2020, 11: 1083.
12. Ming-Qing Tang, et al. Research progress of C-reactive protein analysis. Chinese Journal of Analytical Chemistry, 2020, 48(9): 1121-1130.
13. Tian-Tian Wang, et al. A feasible image-based colorimetric assay using a smartphone RGB camera for point-of-care monitoring of diabetes. Talanta, 2020, 206: 120211.
14. Qian-Long Wang, et al. Colorimetric determination of the early biomarker hypoxia-inducible factor-1 alpha (HIF-1 ) in circulating exosomes by using a gold seed-coated with aptamer-functionalized Au@Au core-shell peroxidase mimic. Microchimica Acta, 2020, 187(1): 61.
15. Chao-Xi Chen, et al. A new strategy for the preparation of antibody against natural glycoside: With astragaloside IV as an example. Fitoterapia, 2020, 142: 104488.
