
- 李家寶
- 電子郵件:lijb@cib.ac.cn
- 職 稱:青年研究員
- 學(xué) 歷:博士研究生
- 通訊地址:成都市人民南路四段九號(hào)
- 郵 編:610041
個(gè)人簡(jiǎn)歷
????李家寶,博士,青年研究員,碩導(dǎo)。2011年畢業(yè)于中國(guó)科學(xué)院微生物研究所微生物學(xué)專業(yè),獲理學(xué)博士學(xué)位,2012年至今在中國(guó)科學(xué)院成都生物研究所開展研究工作。主要從事有機(jī)廢棄物資源化的微生物機(jī)理研究、合成生物學(xué)與生物制造、以及環(huán)境基因組技術(shù)開發(fā)等工作。主持完成10余項(xiàng)課題,在微生物、生物工程、生態(tài)學(xué)等主流刊物上發(fā)表論文50余篇,他引2500余次,H因子28。
研究方向
(1)有機(jī)廢棄物資源化的微生物機(jī)理:聚焦畜禽糞污、秸稈等有機(jī)廢棄物能源化、肥料化、飼料化過(guò)程的微生物機(jī)理及調(diào)控機(jī)制;?
(2)合成生物學(xué)與生物制造:利用合成生物學(xué)技術(shù)與方法,研究微生物代謝調(diào)控機(jī)制,重構(gòu)或優(yōu)化代謝途徑,提高氨基酸、有機(jī)酸等發(fā)酵產(chǎn)物的產(chǎn)率與效率。?
社會(huì)任職
獲獎(jiǎng)及榮譽(yù)
入選中科院“西部之光”西部青年學(xué)者
入選四川省海外高層次留學(xué)人才
承擔(dān)科研項(xiàng)目情況
1. 國(guó)家科技部重點(diǎn)研發(fā)計(jì)劃子課題:厭氧消化高靈敏失穩(wěn)預(yù)警與精準(zhǔn)控制(2023-2027)
2. 四川省科技廳自然科學(xué)基金面上項(xiàng)目:?jiǎn)渭?xì)胞蛋白酵母D. hansenii菌體合成關(guān)鍵基因的篩選與功能驗(yàn)證(2024-2025)
3. 內(nèi)蒙古自治區(qū)科技計(jì)劃項(xiàng)目課題:沼液一步法生產(chǎn)單細(xì)胞蛋白飼料技術(shù)(2023-2025)
4. 中科院西部之光西部青年學(xué)者A類:高氨氮利用單細(xì)胞蛋白菌Candida utilis的基因工程改造(2022-2024)
5. 國(guó)家自然科學(xué)基金面上項(xiàng)目:山地森林土壤中氨氧化古菌和細(xì)菌、反硝化真菌和細(xì)菌介導(dǎo)的氧化亞氮排放及其作用機(jī)制(2019-2022)
6. 國(guó)家自然科學(xué)基金青年項(xiàng)目:土壤甲烷氧化菌群落在海拔梯度上的空間分異(2015-2017)
7. 國(guó)家自然科學(xué)基金重點(diǎn)項(xiàng)目課題:微生物對(duì)土壤P生物地球化學(xué)循環(huán)的驅(qū)動(dòng)作用(2017-2021)
8. 中科院生物多樣性網(wǎng)絡(luò)項(xiàng)目:土壤微生物多樣性監(jiān)測(cè)(2021-2023)
9. 中國(guó)科學(xué)院繼續(xù)教育培訓(xùn)項(xiàng)目:生物信息學(xué)與生態(tài)統(tǒng)計(jì)(2021-2021)
10. 四川省中央引導(dǎo)地方科技發(fā)展專項(xiàng)項(xiàng)目:廚余垃圾定向腐殖化過(guò)程及微生物機(jī)理研究(2020-2021)
11. 中國(guó)科學(xué)院“十三五”信息化專項(xiàng)項(xiàng)目:環(huán)境微生物多樣性重點(diǎn)數(shù)據(jù)庫(kù)建設(shè)與應(yīng)用(2018-2020)
12. 四川省應(yīng)用基礎(chǔ)研究項(xiàng)目:新型金屬有機(jī)骨架材料(MOFs)提高甲烷發(fā)酵速率的關(guān)鍵材料學(xué)特征及其微生物學(xué)機(jī)制(2017-2018)
13. 中科院重點(diǎn)實(shí)驗(yàn)室青年創(chuàng)新團(tuán)隊(duì):畜禽糞污梯級(jí)資源回收(2016-2021)
14. 中科院重點(diǎn)實(shí)驗(yàn)室開放課題:新型產(chǎn)甲烷促進(jìn)材料的篩選及其微生物學(xué)機(jī)制(2016-2018)
15. 國(guó)家科技支撐計(jì)劃課題:果蔬廢棄物厭氧消化工藝及裝備研究(2014-2016)
16. 國(guó)家科技部973課題:產(chǎn)甲烷系統(tǒng)微生物群落協(xié)同作用機(jī)制解析(2013-2017)
17. 企業(yè)委托項(xiàng)目:植物葉片內(nèi)生真菌群落分析(2016-2017)
18. 企業(yè)委托項(xiàng)目:土壤真菌群落多樣性分析(2015-2016)
19. 企業(yè)委托項(xiàng)目:異育銀鯽養(yǎng)殖環(huán)境及腸道微生物群落分析(2015-2016)
代表論著
Xiong, W., Li, J.*, Liu, J., Li, C., He, Z., Li, X. 2024. Quantification of microbially induced soil N2O emissions by an inhibitory cocktail in mountain forest ecosystems. Geoderma, 443:? 116835
Li C., Tu B., Kou Y., Wang Y., Li X., Wang J. and Li J.* (2021). The assembly of methanotrophic communities regulated by soil pH in a mountain ecosystem. CATENA 196: 104883. CATENA. 2020.104883
Li J., Xie T., Zhu H., Zhou J., Li C., Xiong W., Xu L., Wu Y., He Z. and Li X. (2021). Alkaline phosphatase activity mediates soil organic phosphorus mineralization in a subalpine forest ecosystem. Geoderma 404: 115376
Li J., Li C., Kou Y., Yao M., He Z. and Li X. (2020). Distinct mechanisms shape soil bacterial and fungal co-occurrence networks in a mountain ecosystem. FEMS Microbiology Ecology 96: doi: 10.1093/femsec/fiaa030
Li J., Shen Z., Li C., Kou Y., Wang Y., Tu B., Zhang S. and Li X. (2018). Stair-Step Pattern of Soil Bacterial Diversity Mainly Driven by pH and Vegetation Types Along the Elevational Gradients of Gongga Mountain, China. Frontiers in Microbiology 9:? doi: 10.3389/fmicb.2018.00569
Li J., Rui J., Yao M., Zhang S., Yan X., Wang Y., Yan Z. and Li X. (2015). Substrate Type and Free Ammonia Determine Bacterial Community Structure in Full-Scale Mesophilic Anaerobic Digesters Treating Cattle or Swine Manure. Frontiers in Microbiology 6: 1337
Li J., Rui J., Pei Z., Sun X., Zhang S., Yan Z., Wang Y., Liu X., Zheng T. and Li X. (2014). Straw- and slurry-associated prokaryotic communities differ during co-fermentation of straw and swine manure. Applied Microbiology and Biotechnology 98: 4771-4780
Li J., Cai S., Luo Y. and Dong X. (2011). Three feruloyl esterases in Cellulosilyticum ruminicola H1 act synergistically to hydrolyze esterified polysaccharides. Applied and Environmental Microbiology 77: 6141-6147
Zhang M., Lin Q., Rui J., Li J.* and Li X. (2017). Ammonium inhibition through the decoupling of acidification process and methanogenesis in anaerobic digester revealed by high throughput sequencing. Biotechnology Letters 39: 247-252
Wang Y., Li H., Li J.* and Li X.* (2017). The diversity and co-occurrence patterns of diazotrophs in the steppes of Inner Mongolia. CATENA 157: 130-138
Lin Q., De Vrieze J., He G., Li X. and Li J.* (2016). Temperature regulates methane production through the function centralization of microbial community in anaerobic digestion. Bioresource Technology 216: 150-158
Lin Q., He G., Rui J., Fang X., Tao Y., Li J.* and Li X..* (2016). Microorganism-regulated mechanisms of temperature effects on the performance of anaerobic digestion. Microbial Cell Factories 15: 96
Tu Q.#, Li J.#, Shi Z., Chen Y., Lin L., Li J., Wang H., Yan J., Zhou Q., Li X., Li L., Zhou J. and He Z. (2017). HuMiChip2 for strain level identification and functional profiling of human microbiomes. Applied Microbiology and Biotechnology 101: 423-435
Rui J.#, Li J.#, Wang S., An J., Liu W.T., Lin Q. and Yang Y. (2015). Responses of Bacterial Communities to Simulated Climate Changes in Alpine Meadow Soil of the Qinghai-Tibet Plateau. Applied and Environmental Microbiology 81: 6070-6077
Rui J.#, Li J.#, Zhang S., Yan X., Wang Y. and Li X. (2015). The core populations and co-occurrence patterns of prokaryotic communities in household biogas digesters. Biotechnology for Biofuels 8: 158
Tao Y.#, Li J.#, Rui J., Xu Z., Zhou Y., Hu X., Wang X., Liu M., Li D. and Li X. (2014). Prokaryotic communities in pit mud from different-aged cellars used for the production of Chinese strong-flavored liquor. Applied and Environmental Microbiology 80: 2254-2260
張小元, 李香真, 李家寶* (2016). 微生物互營(yíng)產(chǎn)甲烷研究進(jìn)展. 應(yīng)用與環(huán)境生物學(xué)報(bào) 22: 156-166
李家寶, 芮俊鵬, 張時(shí)恒, 孫曉日, 閆志英, 劉曉風(fēng), 鄭濤, 李香真 (2014). 原核微生物菌群的空間分異增強(qiáng)秸稈-豬糞混合發(fā)酵效率. 化工學(xué)報(bào) 65: 1792-1799